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Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases

July 10, 2018

Vol 4 | Issue 2 | July-Dec 2018 | Page 11-13 | Mahfooz Basha Mohamed, Jayasree Kattoor, Kusumakumary Parukuttyamma, Geetha Narayanan, Anitha Mathews, Thara Somanathan. Authors: Mahfooz Basha Mohamed [1], Jayasree Kattoor [2], Kusumakumary Parukuttyamma [3], Geetha Narayanan [4], Anitha Mathews [2], Thara Somanathan [2]. [1] Department of Laboratory Medicine, GKNM Hospital, Coimbatore 641006, Tamil […]

Spectrum of Bone and Soft Tissue Tumors in A Tertiary Cancer Institute in Eastern India

July 10, 2018

Vol 4 | Issue 2 | July-Dec 2018 | Page 7-10 | Ashwini Natekar, Gaurav Gupta, Subhasis Basu. Authors: Ashwini Natekar [1], Gaurav Gupta [1], Subhasis Basu [1]. [1] Dept of Pathology, Chittaranjan national cancer institute, Kolkata, India Address of Correspondence Dr. Ashwini Natekar, Dept of Pathology, Chittaranjan national cancer institute, Kolkata, India Abstract Introduction: […]

Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases

July 10, 2018

Spectrum of Bone and Soft Tissue Tumors in A Tertiary Cancer Institute in Eastern India

July 10, 2018

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Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases

July 10, 2018

Vol 4 | Issue 2 | July-Dec 2018 | Page 11-13 | Mahfooz Basha Mohamed, Jayasree Kattoor, Kusumakumary Parukuttyamma, Geetha Narayanan, Anitha Mathews, Thara Somanathan.

Authors: Mahfooz Basha Mohamed [1], Jayasree Kattoor [2], Kusumakumary Parukuttyamma [3], Geetha Narayanan [4], Anitha Mathews [2], Thara Somanathan [2].

[1] Department of Laboratory Medicine, GKNM Hospital, Coimbatore 641006, Tamil Nadu, India.
[2] Department of Pathology, Regional Cancer Centre, Trivandrum 695011, Kerala, India.
[3] Department of Paediatric Oncology, Regional Cancer Centre, Trivandrum 695011, Kerala, India.
[4] Department of Medical Oncology, Regional Cancer Centre, Trivandrum 695011, Kerala.

Address of Correspondence
Dr. JayasreeKattoor,
Department of Pathology, Regional Cancer Centre, Trivandrum-695011, Kerala, India.
Email: jayasreeramdas@gmail.com

Abstract

Osteosarcoma is the most common primary malignant tumor of bone, usually arising from the metaphysis of the long bones around the knee joint. In 6-13% cases they are located in the head and neck region, of which maxilla and mandible are the most common sites. Osteosarcoma involving the extra-gnathic craniofacial bones account for less than 2% cases. We report eight such cases of osteosarcoma involving this unusual location in the last three years (2011 -2014) and present their clinicopathological profile. Seven patients were under 15 years of age and one patient was 37 years old. Out of the eight cases, four were males and four were females. The location of the tumor included occipital bone, parietal bone, external auditory canal, nasal bone and mastoid. Two patients presented as multicenteric disease with multiple lesions in the skull and elsewhere. Two patients succumbed to the disease while five patients are on follow up. One patient was lost to follow up.A complete en-bloc dissection of the tumor with free margins is a challenge for the operating surgeons. Radiologically they can simulate non-neoplastic lesions or benign tumors as well.These tumors pose a unique therapeutic challenge owing to their unusual location and require a multidisciplinary team approach for management of the patient.
Keywords: Extragnathic, skull, bone, osteosarcoma.

References

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How to Cite this article: Mohamed MB, Kattoor J, Parukuttyamma K, Narayanan G, Mathews A, Somanathan T. Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases. Journal of Bone and Soft Tissue Tumors July-Dec 2018;4(2): 11-13.

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Spectrum of Bone and Soft Tissue Tumors in A Tertiary Cancer Institute in Eastern India

July 10, 2018

Vol 4 | Issue 2 | July-Dec 2018 | Page 7-10 | Ashwini Natekar, Gaurav Gupta, Subhasis Basu.

Authors: Ashwini Natekar [1], Gaurav Gupta [1], Subhasis Basu [1].

[1] Dept of Pathology, Chittaranjan national cancer institute, Kolkata, India

Address of Correspondence
Dr. Ashwini Natekar,
Dept of Pathology, Chittaranjan national cancer institute, Kolkata, India

Abstract

Introduction: Bone and soft tissue tumours are uncommon tumours that can affect any age group. Soft tissue tumors are said to be heterogeneous group of mesenchymal malignancies. Primary bone sarcomas are rare tumors, comprising approximately 0.2% of all cancers. Their true incidence is difficult to estimate because of their rarity.[1]The outcome of the disease depends on the age and time at diagnosis.
Material and Methods: A study was carried out in department of pathology in tertiary cancer institute in East India from December 2015 to September 2017. A total of 60 cases were included in the study. Clinical and radiological details of patients were noted along with gross specimen findings and microscopic examination of H &E stained slides. IHC was also carried out for confirmatory diagnosis.
Aims and Objecctives: 1- To study the histological spectrum of bone and soft tissue tumors in a tertiary cancer institute in Eastern India
2- To study gender distribution and site distributionof bone and soft tissue tumors
Results: Out of the total 60 cases studied 24 cases were of bone and cartilaginous tumours and 36 cases included were of soft tissue tumors. Benign tumors comprised of 08 cases (13.3%) and malignant tumors accounted to 52 cases (86.7%). Age of the patients ranged from 10 to 80 years. Male female ratio was 1.4:1.
Conclusion: Multimodal therapies of treatment is practiced for bone and soft tissue tumors. Early detection and treatment is essential for diagnosis of these malignant tumors. Molecular studies are most important in diagnosing, classifying and also prognosticating bone and soft tissue tumors.
Keywords: bone tumors, soft tissue tumors, histology.

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How to Cite this article: Ashwini Natekar A, Gupta G, Basu S. Spectrum of Bone and Soft Tissue Tumors in A Tertiary Cancer Institute in Eastern India. Journal of Bone and Soft Tissue Tumors July – Dec 2018;4(2): 7-10.

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Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases

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Spectrum of Bone and Soft Tissue Tumors in A Tertiary Cancer Institute in Eastern India

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Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases

Authors: Mahfooz Basha Mohamed [1], Jayasree Kattoor [2], Kusumakumary Parukuttyamma [3], Geetha Narayanan [4], Anitha Mathews [2], Thara Somanathan [2].

Abstract

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Spectrum of Bone and Soft Tissue Tumors in A Tertiary Cancer Institute in Eastern India

Authors: Ashwini Natekar [1], Gaurav Gupta [1], Subhasis Basu [1].

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Authors: Mahfooz Basha Mohamed [1], Jayasree Kattoor [2], Kusumakumary Parukuttyamma [3], Geetha Narayanan [4], Anitha Mathews [2], Thara Somanathan [2].

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Authors: Ashwini Natekar [1], Gaurav Gupta [1], Subhasis Basu [1].

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