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Retrospective Study of Seven Patients with Tumoral Calcinosis

May 10, 2020

Original Article | Volume 6 | Issue 2 | JBST May-August 2020 | Page 12-16 | Kshitij Manerikar, Abhijeet Salunke, Jaymin V. Shah, Mayur Kamani, Shashank Pandya. DOI: 10.13107/jbst.2020.v06i02.25 Author: Kshitij Manerikar[1], Abhijeet Salunke[1], Jaymin V. Shah[1], Mayur Kamani[1], Shashank Pandya[1] [1]Department of Surgical Oncology, Gujarat Cancer Research and Institute, Ahmedabad, Gujarat, India. Address of […]

Clear Cell Sarcoma: A Rare Aggressive Tumor with Potential Diagnostic Challenge

May 10, 2020

Original Article | Volume 6 | Issue 2 | JBST May-August 2020 | Page 9-11 | Adam Goldman, Matthew Doscher, Neil Lancaster, Paul Lamberti. DOI: 10.13107/jbst.2020.v06i02.24 Author: Adam Goldman[1], Matthew Doscher[1], Neil Lancaster[2], Paul Lamberti[1] [1]Department of Orthopaedics, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA, [2]Department of Orthopaedics, Franciscan Health- Olympia […]

Retrospective Study of Seven Patients with Tumoral Calcinosis

May 10, 2020

Clear Cell Sarcoma: A Rare Aggressive Tumor with Potential Diagnostic Challenge

May 10, 2020

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Retrospective Study of Seven Patients with Tumoral Calcinosis

May 10, 2020

Author: Kshitij Manerikar[1], Abhijeet Salunke[1], Jaymin V. Shah[1], Mayur Kamani[1], Shashank Pandya[1]

[1]Department of Surgical Oncology, Gujarat Cancer Research and Institute, Ahmedabad, Gujarat, India.

Address of Correspondence
Dr. Kshitij Manerikar,
A-302, Divyadeep, Ram Mandir Road, TPS-3, Borivali West, Mumbai – 400 092, Maharashtra, India.
E-mail: drkshitijmanerikar@gmail.com

Abstract

Introduction: Calcium deposition in the skin has been termed as calcinosis cutis. Tumoral calcinosis is idiopathic form of calcinosis cutis. Etiology of idiopathic calcinosis cutis is unknown. It is characterized by periarticular deposition of amorphous calcium salts around large joints. Our diligent search through literature could not find any consensus on the etiopathogenesis and treatment modalities for tumoral calcinosis.
Materials and Methods: A retrospective study of seven patients of tumoral calcinosis treated with complete surgical excision over a period of 1 year was done. Demographic details were compiled. Routine blood investigations were performed. All patients underwent radiographs and magnetic resonance imaging (MRI) scans of involved part. We did not perform computed tomography (CT) or bone scan in any of our patients. All seven patients underwent surgery and were followed up till 2 years.
Results: In our study, five were female and two were male patients ranging from 31 to 76 years. Size of swelling varied from 2 to 15 cm. Most common location was hip. Serum calcium, phosphorus, and alkaline phosphatase were normal in all patients. Radiographs showed well-outlined periarticular cluster of calcifications in the soft tissues around joint. MRI revealed round to oval multiple cystic lesions around the affected region, but not involving the joint.
Conclusion: Tumoral calcinosis is always the diagnosis of exclusion. It can be normophosphatemic or hypophosphatemic subtype. Large joints are more commonly affected. One can rely on radiographs for diagnosis. MRI for knowing exact location of lesion, its relationship with adjacent structures and planning of surgery is advocated. Complete surgical excision is the only optimum treatment of tumoral calcinosis.
Keywords: Amorphous calcium phosphate, hyperphosphatemia, X-ray film, hip joint, calcinosis, magnetic resonance imaging.

Reference:
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How to Cite this article: Manerikar K, Salunke A, Shah JV, Kamani M, Pandya S | Retrospective Study of Seven Patients with Tumoral Calcinosis | Journal of Bone and Soft Tissue Tumors | May-August 2020; 6(2): 12-16.

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Clear Cell Sarcoma: A Rare Aggressive Tumor with Potential Diagnostic Challenge

May 10, 2020

Author: Adam Goldman[1], Matthew Doscher[1], Neil Lancaster[2], Paul Lamberti[1]

[1]Department of Orthopaedics, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA,
[2]Department of Orthopaedics, Franciscan Health- Olympia Fields, Illinois, USA.

Address of Correspondence
Dr. Adam Goldman,
Orthopedic Surgery Resident, Franciscan Health Olympia Fields
20201 S. Crawford Ave, Olympia Fields, IL 60461.
E-mail: adamgoldman91@gmail.com

Abstract

Introduction: Synovial sarcomas of the hand are extremely rare, high grade, slow growing, malignant soft-tissue neoplasms. They represent only a fraction of soft-tissue sarcomas, are usually found in the lower extremities around tendon sheaths, bursae, and joint capsules, and carry a significant risk for recurrence and eventual metastasis to the lymph nodes and lungs. There are limited reports of synovial sarcomas of the hand.
Case Report: A 67-year-old male presented with a slow-growing soft-tissue mass of the proximal right long finger over the course of one year. Initial excision was performed, which provided a diagnosis of monophasic synovial cell sarcoma. Subsequently, the patient underwent further staging with an eventual ray resection of the right long finger and an index ray transfer.
Conclusion: There are unique approaches to a patient with a highly malignant neoplasm in the hand. By performing a ray resection and index ray transfer, the patient was spared the potential side effects of radiation therapy and provided a quality functional and cosmetic outcome. The patient returned to work 4 weeks postoperatively. To the best of our knowledge, this treatment has not been used for a synovial sarcoma of the hand.
Keywords: Hand, synovial sarcoma, soft-tissue sarcoma, soft-tissue neoplasms

Reference:
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9. Italiano A, Penel N, Robin YM, Bui B, Le Cesne A, Piperno-Neumann S, et al. Neo/adjuvant chemotherapy does not improve outcome in resected primary synovial sarcoma: A study of the French sarcoma group. Ann Oncol 2009;20:425-30.
10. Maia DC, Menezes CK, Bastos TC, de Lima Ferreira LC, Francesconi F. Poorly differentiated synovial sarcoma in the wrist: Case report. An Bras Dermatol 2014;89:816-18.
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How to Cite this article: Goldman A, Doscher M, Lancaster N, Lamberti P | Clear Cell Sarcoma: A Rare Aggressive Tumor with Potential Diagnostic Challenge | Journal of Bone and Soft Tissue Tumors | May-August 2020; 6(2): 9-11.

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Retrospective Study of Seven Patients with Tumoral Calcinosis

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Clear Cell Sarcoma: A Rare Aggressive Tumor with Potential Diagnostic Challenge

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