Local Recurrences of Giant Cell Tumor of Bones after Extended Surgical Curettage – A Retrospective Cohort Study
Original Article | Volume 6 | Issue 1 | JBST January-April 2020 | Page 9-12 | DOI: 10.13107/jbst.2020.v06i01.007
Author: Dominic K Puthur , Dijoe Davis , N Sanjay 
1. Department of Orthopaedics, Amala Institute of Medical Sciences, Thrissur, Kerala, India.
Address of Correspondence
Dr. Dijoe Davis,
Department of Orthopaedics, Amala Institute of Medical Sciences,
Cloud Nine, Kollannur Villas, Jasmin Road, Near Water Tank Street
Nehrunagar, Kuriachira P.O, Thrissur – 680 006, Kerala, India.
Introduction: Giant cell tumor of bone (GCTB) is a locally aggressive tumor well known for recurrence after surgical treatment. Local recurrence rate ranged from 10 to 25%. The objectives of this study are to find out the incidence of recurrence in GCT after extended surgical curettage, factors affecting recurrence, and also to find the best modality of treatment available for the recurred GCT.
Materials and Methods: It was a retrospective cohort study of 225 patients diagnosed and treated by extended surgical curettage in the Orthopaedic Department of a Tertiary Care Hospital in South India, between January 2003 and December 2017. Patients were followed up clinically and radiologically for diagnosis of recurrence. Factors affecting the recurrence were analyzed. These recurrent cases were further followed up. IBM SPSS v23 was used for data analysis such as age, gender, site of lesion and side, and material used to fill the defect after curettage. Descriptive statistics was elaborated in the form of means and standard deviations for continuous variables and frequencies and percentages for categorical variables. Fisher’s exact test is used for comparison.
Results: Recurrence was found in 27 patients of 225 cases of GCTB treated by extended surgical curettage. These include 9 of 135 cases initially treated by extended curettage and bone cement and 18 of 88 cases initially treated by curettage and bone graft. Recurrence was found to be more common in males than females.
Conclusions: Local recurrence is significantly lower in patients treated by cementation following extended surgical curettage than bone graft which makes bone cement as a better filling material with regard to recurrence.
Keywords: Giant cell tumor, Curettage, Bone cement, Bone graft, South India.
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|How to Cite this article: Puthur D K, Davis D, Sanjay N | Local Recurrences of Giant Cell Tumor of Bones After Extended Surgical Curettage– A Retrospective Cohort Study | Journal of Bone and Soft Tissue Tumors | Jan-Apr 2020; 6(1): 9-12.|