Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases
Vol 4 | Issue 2 | July-Dec 2018 | Page 11-13 | Mahfooz Basha Mohamed, Jayasree Kattoor, Kusumakumary Parukuttyamma, Geetha Narayanan, Anitha Mathews, Thara Somanathan.
Authors: Mahfooz Basha Mohamed [1], Jayasree Kattoor [2], Kusumakumary Parukuttyamma [3], Geetha Narayanan [4], Anitha Mathews [2], Thara Somanathan [2].
[1] Department of Laboratory Medicine, GKNM Hospital, Coimbatore 641006, Tamil Nadu, India.
[2] Department of Pathology, Regional Cancer Centre, Trivandrum 695011, Kerala, India.
[3] Department of Paediatric Oncology, Regional Cancer Centre, Trivandrum 695011, Kerala, India.
[4] Department of Medical Oncology, Regional Cancer Centre, Trivandrum 695011, Kerala.
Address of Correspondence
Dr. JayasreeKattoor,
Department of Pathology, Regional Cancer Centre, Trivandrum-695011, Kerala, India.
Email: jayasreeramdas@gmail.com
Abstract
Osteosarcoma is the most common primary malignant tumor of bone, usually arising from the metaphysis of the long bones around the knee joint. In 6-13% cases they are located in the head and neck region, of which maxilla and mandible are the most common sites. Osteosarcoma involving the extra-gnathic craniofacial bones account for less than 2% cases. We report eight such cases of osteosarcoma involving this unusual location in the last three years (2011 -2014) and present their clinicopathological profile. Seven patients were under 15 years of age and one patient was 37 years old. Out of the eight cases, four were males and four were females. The location of the tumor included occipital bone, parietal bone, external auditory canal, nasal bone and mastoid. Two patients presented as multicenteric disease with multiple lesions in the skull and elsewhere. Two patients succumbed to the disease while five patients are on follow up. One patient was lost to follow up.A complete en-bloc dissection of the tumor with free margins is a challenge for the operating surgeons. Radiologically they can simulate non-neoplastic lesions or benign tumors as well.These tumors pose a unique therapeutic challenge owing to their unusual location and require a multidisciplinary team approach for management of the patient.
Keywords: Extragnathic, skull, bone, osteosarcoma.
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| How to Cite this article: Mohamed MB, Kattoor J, Parukuttyamma K, Narayanan G, Mathews A, Somanathan T. Osteosarcoma of Extragnathic Skull Bones-clinicopathological Profile of Eight Cases. Journal of Bone and Soft Tissue Tumors July-Dec 2018;4(2): 11-13. |
