Case Report | Volume 7 | Issue 3 | JBST September – December 2021 | Page 13-15 | Chitturi Ramya, Jayasree Kattoor, Narayanan Geetha, Muraleedharan Venugopal. DOI:0.13107/jbst.2021.v07i03.59
Author: Chitturi Ramya , Jayasree Kattoor , Narayanan Geetha , Muraleedharan Venugopal 
 Department of Pathology, NRI Medical College, Chinakakani, Andhra Pradesh, India.
 Department of Pathology, Regional Cancer Centre, Trivandrum, Kerala, India.
 Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India.
 Department of Radiology, Regional Cancer Centre, Trivandrum, Kerala, India.
Address of Correspondence
Dr. Jayasree Kattoor,
Department of Pathology, Regional Cancer Centre, Trivandrum, Kerala, India.
Background: Vertebral osteosarcoma is rare, accounting for 3%–5% of all osteosarcomas. It tends to occur in a slightly older age group. The prognosis is poor compared to osteosarcoma of extremities.
Case Report: We present five cases of vertebral osteosarcomas. The patient’s age ranged from 16 years to 54 years. There were four females and one male. They presented with pain, swelling, or weakness of limbs. Destructive lesions, mixed lytic and sclerotic lesions involving vertebral bodies, and/or pedicles were seen on imaging. A definitive diagnosis could not be made in two cases. On histopathological examination, all the cases turned out to be osteosarcomas.
Conclusion: Osteosarcoma of vertebrae has high rate of recurrence, metastasis, and mortality. Differentiation of vertebral osteosarcoma from other common bony lesions involving the spine is of utmost importance as the treatment is entirely different. Combination therapies including surgery, radiation, and chemotherapy achieve adequate short-term survival rates for vertebral osteosarcoma.
Keywords: Osteosarcoma, Spine, Vertebra.
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|How to Cite this article: Ramya C, Kattoor J, Geetha N, Venugopal M | Vertebral Osteosarcoma – A Report of Five Cases. | Journal of Bone and Soft Tissue Tumors | Sep-Dec 2021; 7(3): 13-15.|