Primary Leiomyosarcoma of the Hip Bone: A Case Report and Literature Review

Vol 5 | Issue 3 | September – December 2019 | page: 5-7 | Dr. Francisco de Assis Serra Baima Filho.

Author: Francisco de Assis Serra Baima Filho [1].

[1] Department of Orthopedic Oncology, Aldenora Bello Oncology Institute of Maranhao, Brazil.

Address of Correspondence
Dr. Francisco de Assis Serra Baima Filho,
Department of Orthopedic Oncology, Aldenora Bello Orthopedic Oncology Institute of Maranhao (IMOAB), Brazil.


Introduction: Leiomyosarcoma is a rare smooth muscle mesenchymal neoplasm. The primary bone form is the rarest subtype. It mainly affects middle aged and female people. The most common complaint is the presence of a mass accompanied by pain. Diagnostic imaging and biopsy are required. The gold standard treatment is resection with oncologic margin.
Case Report: A 20-year-old female had a history of tumor mass and left hip pain beginning in September 2018.The patient showed the radiographic examination, osteolytic lesion of the left hip, and computed tomography scan of the abdomen with a solid expansive process measuring 15.8 cm left hip destruction and absence of organ damage. Biopsy and immunohistochemical result of leiomyosarcoma. Neoadjuvant chemotherapy was not effective. Thus, we opted for tumor resection with internal hemipelvectomy Type I.
Conclusion: Primary bone leiomyosarcoma is a rare malignant neoplasm which only shows tumoral resection with oncological margins as a curative treatment, thus the need for early diagnosis to allow adequate resection and lower patient morbidity.
Keywords: Leiomyosarcoma, case reports, rare diseases, literature review.


1. Gordon RW, Tirumani SH, Kurra V, Shinagare AB, Jagannathan JP, Hornick JL, et al. MRI, MDCT features, and clinical outcome of extremity leiomyosarcomas: Experience in 47 patients. Skeletal Radiol2014;43:615- 22.
2. Tahara K, Yamashita K, Hiwatashi A, Togao O, Kikuchi K, Endo M, et al. MR imaging findings of a leiomyosarcoma of the thoracic spine: A case report. Clin Neuroradiol 2016;26:229-33.
3. Mori T, Nakayama R, Endo M, Hiraga H, Tomita M, Fukase N, et al. Fortyeight cases of leiomyosarcoma of bone in Japan: A multicenter study from
the Japanese musculoskeletal oncology group. J Surg Oncol 2016;114:495-500.
4. Rekhi B, Kaur A, Puri A, Desai S, Jambhekar NA. Primary leiomyosarcoma of bone–a clinicopathologic study of 8 uncommon cases
with immunohistochemical analysis and clinical outcomes. Ann Diagn Pathol2011;15:147-56.
5. Potsi M, Stavrinou P, Patsinakidis N, Hatzibougias D, Foroglou N, Karayanopoulou G, et al. Primary osseous leiomyosarcoma of the spine: A
rare entity–case report and review of the literature. J Neurol Surg A Cent Eur Neurosurg2012;73:238-42.
6. Yang Y, Ma L, Li L, Liu H. Primary leiomyosarcoma of the spine: A case report and literature review. Medicine (Baltimore) 2017;96:e6227.
7. Zumárraga JP, Arouca MM, Baptista AM, Caiero MT, Rubio DE, Camargo OP. Primary leiomyosarcoma of bone: Clinicopathologic and
prognostic factors analysis in a single institution. Acta Ortopédica Bras 2019;27:152-5.
8. Recine F, Bongiovanni A, Casadei R, Pieri F, Riva N, De Vita A, et al. Primary leiomyosarcoma of the bone: A case report and a review of the literature. Medicine (Baltimore) 2017;96:e8545.

How to Cite this article:  De Assis Serra Baima Filho F | Primary Leiomyosarcoma of the Hip Bone: A Case Report and Literature Review | Journal of Bone and Soft Tissue Tumors | Sep-Dec 2019;5(3): 5-7.

(Abstract Full Text HTML) (Download PDF)